Helicobacter Pylori Genome Project (HpGP)
Helicobacter Pylori Genome Project (HpGP)

Objective: to study the genetic variations of H. pylori strains based on samples from chronically infected people to determine the characteristics of strains that can lead to serious stomach problems or stomach cancer.

Dates: 2016-2021

Funding: initiative

Consortium members: Greece, Honduras, Latvia, Lithuania, Mexico, Peru, Taiwan, Brazil, Canada, Chile, Egypt, Guatemala, Bulgaria, Romania, India, Iran, Italy, Japan, Kazakhstan, Kyrgyzstan, Korea, Kuwait, Spain, Sudan, Sweden, Turkey and the United States.

Participants from Kyrgyzstan: Marina Moldobaeva-MD, Professor, Head of the Department of Propaedeutics of Internal Diseases with the course of Endocrinology; Rakhat Attokurova-Assistant of the Department.

Participation in the Research: biomaterial was collected from 40 patients with chronic gastritis, which was sent to the United States for further study. The collection, storage and transport of biomaterials was carried out in accordance with the Sydney Protocol. The degree of atrophy was determined by the OLGA system. Currently, the genome is being sequenced in the United States, and the results are being processed until May-the month of 2021. In September 2021, it is planned to publish an article on the results of the research of this project.

 

   

Nr

Patient nr

Origin

Culture

Hp status

Diagnosis

1

ChMA

Bishkek

positive

Hypertrophic gastritis OLGA II

2

DKI

Bishkek

positive

Hypertrophic gastritis. Duodenitis OLGA II

3

AAS

Bishkek

positive

Superficial gastroduodenitis OLGA II

4

KKA

Bishkek

positive

Hypertrophic gastritis OLGA 0

5

SAS

Bishkek

positive

Erosive gastritis OLGA II

6

KSM

Bishkek

positive

Erosive gastritis OLGA II

7

SJZ

Bishkek

positive

Superficial gastritis OLGA III

8

DKA

Bishkek

positive

Superficial gastritis OLGA IV

9

MAK

Bishkek

positive

Superficial gastritis OLGA II

10

ABN

Bishkek

positive

Superficial gastritis OLGA IV

11

OAM

Bishkek

positive

Superficial gastritis OLGA II

12

MTSh

Bishkek

positive

Superficial gastritis OLGA IV

13

BSS

Bishkek

positive

Superficial gastritis OLGA IV

14

KRA

Bishkek

positive

Antrum erosion OLGA III

15

MB

Bishkek

positive

Superficial gastritis OLGA IV

16

BMK

Bishkek

positive

Superficial gastritis OLGA III

17

MUM

Bishkek

positive

Hypertrophic gastritis OLGA II

18

NES

Bishkek

positive

Hypertrophic gastritis OLGA I

19

BMB

Bishkek

positive

Superficial gastritis OLGA IV

20

KKA

Bishkek

positive

Superficial gastritis OLGA IV

21

UII

Bishkek

positive

Hypertrophic gastritis OLGA IV

22

BUJ

Bishkek

positive

Hypertrophic gastritis OLGA II

23

ShSK

Bishkek

positive

Hypertrophic gastritis OLGA III

24

SDM

Bishkek

positive

Superficial gastritis OLGA III

25

PUS

Bishkek

positive

Superficial gastritis OLGA III

26

PB

Bishkek

positive

Superficial gastritis OLGA II

27

AJM

Bishkek

positive

Superficial gastritis OLGA IV

28

NMS

Bishkek

positive

Superficial gastritis OLGA III

29

JBA

Bishkek

positive

Superficial gastritis, DGR OLGA IV

30

KDT

Bishkek

positive

Superficial gastritis OLGA IV

31

MNK

Bishkek

positive

Hypertrophic gastritis OLGA  III

32

MAS

Bishkek

positive

Superficial gastritis OLGA IV

33

NMM

Bishkek

positive

Hypertrophic gastritis OLGA  III

34

JM

Bishkek

positive

Hypertrophic gastritis OLGA  III

35

ShUM

Bishkek

positive

Superficial gastritis OLGA IV

36

II

Bishkek

positive

Hypertrophic gastritis OLGA  IV

37

TDT

Bishkek

positive

Hypertrophic gastritis OLGA  IV

38

BAA

Bishkek

positive

Superficial gastritis OLGA II

39

KND

Bishkek

positive

Superficial gastritis OLGA IV

40

SKhS

Bishkek

positive

Superficial gastritis. DGR OLGA IV

Ссылка на сайт: https://clinicaltrials.gov/ct2/show/study/NCT02788214?term=HpGP&draw=2&rank=1